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Regenerative Medicine & IV Therapy located in Honolulu , HI


Hormonal imbalances can lead to frustrating symptoms like low sex drive, issues with sexual performance, disruptions in sleep, mental fogginess, and depression. Fortunately, Jené Ferrante, ND, and the team at Hawaii Natural Medicine provide bioidentical hormone replacement therapy (BHRT) treatments to patients aged 20 and older in Honolulu, Hawaii. BioTE® hormone therapy, which uses hormones created from natural plant sources, is a painless, efficient procedure that can improve your energy, sexual drive, mental clarity, and overall well-being. Dr. Jene Ferrante is one of four certified Biote providers on Oahu.  Biote is well known for its quality control of hormone pellet production and stricter than industry standards.  To learn more, call the friendly staff today or schedule a consultation online.

What is BHRT?

Bioidentical hormone replacement therapy (BHRT) uses manufactured hormones to replicate your body’s natural hormones. 

As you age, it's normal to experience hormone loss and imbalance, which can lead to side effects like sexual dysfunction, fatigue, depression, infertility, and hair loss. 

Hawaii Natural Medicine offers BioTE® hormone therapy, which utilizes hormones created from natural plant sources. Hormones come in pellet form and are around the size of a grain of rice. The team inserts the pellets under your skin during a painless procedure.

What are the benefits of BHRT?

Several forms of hormone therapy, like BioTE®, can address unwanted symptoms that come with hormonal imbalances. This may include improving low energy, vaginal dryness, low libido, thinning hair, and weight gain. Gender-affirming hormone therapy can help you address the physical aspects of your gender.

At Hawaii Natural Medicine, a holistic BHRT plan can:

  • Improve energy 
  • Increase muscle strength 
  • Reduce body fat
  • Restore mental clarity and memory 
  • Improve sleeping patterns and mood
  • Address depression and anxiety 
  • Increase sexual desire 
  • Alleviate sexual dysfunction
  • Improve menopause symptoms  
  • Decrease risk of heart disease and osteoporosis
  • Reduce joint pain


The team communicates with you about any risks associated with BHRT and common side effects that may include weight gain, fatigue, bloating, spotting, headaches, and breast tenderness. 

What can I expect from BHRT treatment?

Before starting treatment, the team considers your medical history, symptoms, lab tests, hormone levels, and body mass index (BMI). These factors determine the appropriate dose of hormone pellets.    

The team performs the BioTE procedure in the office, which takes 4-10 minutes. 

Your provider uses local anesthesia to numb the incision area. They then insert 1-12 hormone pellets subcutaneously under the fatty lining in your upper buttocks and close the incision with sterile tape strips. 

Your body directly absorbs the hormones through your bloodstream and regulates usage as needed — a major benefit of hormone therapy. You also don’t have to keep up with daily creams, gels, or oral medications.

Because your body is adjusting to new levels of hormones, it’s essential to stay in communication with the team about any changes you experience or side effects. They can adjust dosages as needed. 

Pellets can last 3-6 months, depending on your gender, weight, absorption rates, and hormone levels at the time of insertion. Typically, you can receive pellet insertions 2-4 times per year to help keep your hormones optimized and balanced. 

If you’re experiencing side effects of a hormone imbalance like low sex drive, sexual dysfunction, or decreased energy and mood, schedule a hormone therapy consultation with Hawaii Natural Medicine today by phone or online. 


Wellness & Integrative Medicine Disclaimer - All patients react differently to wellness treatments such as HCG, glutathione, chelation, IV therapy, or hormone therapy. There is never a better solution than a physician supervised program that includes proper diet and exercise. These statements have not been evaluated by the Food and Drug Administration. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other healthcare professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician. The treatments we offer will never provide the same results to all patients. Everyone is vastly unique and the results can never be guaranteed. There are too many variables in regards to a patients anatomy and ability to heal or recover.